| Income Tax Disclosure [Abstract] | Period [Axis] |
|---|
2016-01-01 - 2016-12-31 |
|---|
Income Tax Disclosure [Abstract] | |
Schedule of Domestic and Foreign Components of (Loss) Income Before Income Taxes |
|
(In thousands) |
|
Year ended
December 31,
2016 |
|
|
Year ended
December 31,
2015 |
|
|
Year ended
December 31,
2014 |
|
|
Domestic |
|
$ |
(36,454 |
) |
|
$ |
16,284 |
|
|
$ |
25,679 |
|
|
Foreign |
|
|
(5,814 |
) |
|
|
3,085 |
|
|
|
2,330 |
|
|
Total |
|
$ |
(42,268 |
) |
|
$ |
19,369 |
|
|
$ |
28,009 |
|
|
Schedule of Benefit from (Provision for) Income Taxes |
|
(In thousands) |
|
Year ended
December 31,
2016 |
|
|
Year ended
December 31,
2015 |
|
|
Year ended
December 31,
2014 |
|
|
Current: |
|
|
|
|
|
|
|
|
|
|
|
|
|
Federal |
|
$ |
(852 |
) |
|
$ |
(603 |
) |
|
$ |
(1,105 |
) |
|
State |
|
|
(4,517 |
) |
|
|
(2,773 |
) |
|
|
(1,819 |
) |
|
Foreign |
|
|
781 |
|
|
|
(960 |
) |
|
|
(732 |
) |
|
|
|
|
(4,588 |
) |
|
|
(4,336 |
) |
|
|
(3,656 |
) |
|
Deferred: |
|
|
|
|
|
|
|
|
|
|
|
|
|
Federal |
|
|
9,465 |
|
|
|
(2,960 |
) |
|
|
(6,085 |
) |
|
State |
|
|
1,788 |
|
|
|
(1,015 |
) |
|
|
(596 |
) |
|
Foreign |
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
|
|
11,253 |
|
|
|
(3,975 |
) |
|
|
(6,681 |
) |
|
Total benefit from (provision for) income taxes |
|
$ |
6,665 |
|
|
$ |
(8,311 |
) |
|
$ |
(10,337 |
) |
|
Schedule of Reconciliation of the Statutory U.S. Federal Income Tax Rate to the Entity's Effective Income Tax Rate |
|
|
|
Year ended
December 31,
2016 |
|
|
Year ended
December 31,
2015 |
|
|
Year ended
December 31,
2014 |
|
|
U.S. federal statutory tax rate |
|
|
35.0 |
% |
|
|
35.0 |
% |
|
|
35.0 |
% |
|
State and local income taxes |
|
|
(3.8 |
)% |
|
|
13.3 |
% |
|
|
3.7 |
% |
|
Non-deductible payment to prior shareholders |
|
|
— |
|
|
|
15.8 |
% |
|
|
— |
|
|
Foreign income tax |
|
|
1.2 |
% |
|
|
3.2 |
% |
|
|
1.8 |
% |
|
Stock option compensation |
|
|
(3.8 |
)% |
|
|
10.4 |
% |
|
|
4.8 |
% |
|
Stock option shortfall |
|
|
(6.5 |
)% |
|
|
— |
|
|
|
— |
|
|
Research and development and orphan drug credits |
|
|
28.9 |
% |
|
|
(42.9 |
)% |
|
|
(15.5 |
)% |
|
Increase to Uncertain Tax Positions |
|
|
(4.8 |
)% |
|
|
7.1 |
% |
|
|
2.3 |
% |
|
Other nondeductible and permanent differences |
|
|
(1.1 |
)% |
|
|
1.9 |
% |
|
|
2.6 |
% |
|
Valuation allowance |
|
|
(31.6 |
)% |
|
|
(0.9 |
)% |
|
|
2.2 |
% |
|
Transaction Cost |
|
|
(5.9 |
)% |
|
|
— |
|
|
|
— |
|
|
Gain or Loss on Hedging |
|
|
8.2 |
% |
|
|
— |
|
|
|
— |
|
|
Effective income tax rate |
|
|
15.8 |
% |
|
|
42.9 |
% |
|
|
36.9 |
% |
|
Schedule of Deferred Tax Assets and Liabilities |
|
(In thousands) |
|
December 31,
2016 |
|
|
December 31,
2015 |
|
|
Deferred tax assets: |
|
|
|
|
|
|
|
|
|
Net operating loss and other carryforwards |
|
$ |
97,391 |
|
|
$ |
60,889 |
|
|
Tax credits |
|
|
35,489 |
|
|
|
20,778 |
|
|
Deferred revenue |
|
|
11,672 |
|
|
|
13,949 |
|
|
Stock based compensation |
|
|
34,700 |
|
|
|
27,142 |
|
|
Contingent consideration |
|
|
26,543 |
|
|
|
23,298 |
|
|
Employee compensation |
|
|
6,116 |
|
|
|
5,603 |
|
|
Legal reserve |
|
|
2,707 |
|
|
|
— |
|
|
Rebate and returns reserve |
|
|
7,582 |
|
|
|
4,994 |
|
|
Capitalized R&D |
|
|
10,025 |
|
|
|
— |
|
|
Other |
|
|
4,096 |
|
|
|
3,126 |
|
|
Total deferred tax assets |
|
$ |
236,321 |
|
|
$ |
159,779 |
|
|
Valuation allowance |
|
$ |
(63,225 |
) |
|
$ |
(5,277 |
) |
|
Total deferred tax assets net of valuation allowance |
|
$ |
173,096 |
|
|
$ |
154,502 |
|
|
Deferred tax liabilities: |
|
|
|
|
|
|
|
|
|
Intangible assets |
|
|
(245,500 |
) |
|
|
(145,433 |
) |
|
Convertible debt |
|
|
(16,003 |
) |
|
|
(19,087 |
) |
|
Total deferred tax liabilities |
|
$ |
(261,503 |
) |
|
$ |
(164,520 |
) |
|
Net deferred tax liability |
|
$ |
(88,407 |
) |
|
$ |
(10,018 |
) |
|
Schedule of Reconciliation of Beginning and Ending Amounts of Unrecognized Tax Benefits |
|
(In thousands) |
|
Year ended
December 31,
2016 |
|
|
Year ended
December 31,
2015 |
|
|
Year ended
December 31,
2014 |
|
|
Beginning of period balance |
|
$ |
4,835 |
|
|
$ |
3,295 |
|
|
$ |
2,244 |
|
|
Increases for tax positions taken during a prior period |
|
|
570 |
|
|
|
308 |
|
|
|
451 |
|
|
Decreases for tax positions taken during a prior period |
|
|
— |
|
|
|
— |
|
|
|
(200 |
) |
|
Increases for tax positions taken during the current period |
|
|
1,451 |
|
|
|
1,232 |
|
|
|
800 |
|
|
Reduction as a result of a lapse of statute of limitations |
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
|
$ |
6,856 |
|
|
$ |
4,835 |
|
|
$ |
3,295 |
|
|